Modulation of gene expression induced by supercritical fluid rosemary extract in colon cancer cells

ABSTRACT: Supercritical rosemary extract (containing 16.90% carnosic acid, 1.90% carnosol and 13.59% volatile compounds) showed antitumor activity on colon cancer cells in vitro. We treated colon cancer cells with the extract and we employed whole genome microarray expression profiling to identify genes potentially involved in its antitumor mechanism of action. We analyzed gene expression of colon cancer SW620 cells after treating during 48h with supercritical rosemary extract at concentrations that cause 50% inhibition of cell viability (30 M-NM-

ORGANISM(S): Homo sapiens

SUBMITTER: MARGARITA GONZALEZ-VALLINAS 

PROVIDER: E-GEOD-56496 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress