Mouse RPE/choroid age comparison - ATLAS arrays
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Leonard Hjelmeland
PROVIDER: E-GEOD-565 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Age-related changes in the transcriptional profile of mouse RPE/choroid.
Ida Hisashi H Boylan Sharon A SA Weigel Andrea L AL Hjelmeland Leonard M LM
Physiological genomics 20031111 3
To evaluate the age-related changes in gene expression occurring in the complex of retinal pigmented epithelium, Bruch's membrane, and choroid (RPE/choroid), we examined the gene expression profiles of young adult (2 mo) and old (24 mo) male C57BL/6 mice. cDNA probe sets from individual animals were synthesized using total RNA isolated from the RPE/choroid of each animal. Probes were amplified using the Clontech SMART system, radioactively labeled, and hybridized to two different Clontech Atlas ...[more]
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