The human miRNA repertoire of different blood compounds

ABSTRACT: Background: MiRNAs from body fluids gain more and more attraction as biomarker candidates. Besides serum, patterns from whole blood are increasingly considered as markers for human pathologies. Usually, the contribution of different cell types to the respective signature remains however unknown. In this study we provide insights into the human miRNome of different compounds of the blood including CD3, CD14, CD15, CD19, CD56 positive cells as well as exosomes. Methods: We measured the miRNA repertoire for each cell type and whole blood for two individuals at three time points over the course of one year in order to provide evidence that the cell type miRNomes can be reproducibly detected. Results: For measurements repeated after 24 hours we found on average correlation of 0.97, even after o

ORGANISM(S): Homo sapiens

SUBMITTER: Christina Backes 

PROVIDER: E-GEOD-56590 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress