The global response regulator RegR controls expression of denitrification genes in Bradyrhizobium japonicum

ABSTRACT: Bradyrhizobium japonicum RegSR regulatory proteins belong to the family of two-component regulatory systems, and orthologs are present in many Proteobacteria where they globally control gene expression mostly in a redox-responsive manner. In this work, we have performed a transcriptional profiling of wild-type and regR mutant cells grown under anoxic denitrifying conditions. The comparative analyses of wild-type and regR strains revealed that almost 620 genes induced in the wild type under denitrifying conditions were regulated (directly or indirectly) by RegR, pointing out the important role of this protein as a global regulator of denitrification. Genes controlled by RegR included nor and nos structural genes encoding nitric oxide and nitrous oxide reductase, respectively, genes encoding

ORGANISM(S): Bradyrhizobium japonicum

SUBMITTER: Hans-Martin Fischer 

PROVIDER: E-GEOD-56668 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress