Functional characterization of the TERRA transcriptome at damaged telomeres

ABSTRACT: We characterize the TERRA transcriptome at normal and TRF2-depleted telomeres by RNA-seq and we demonstrate that TERRA upregulation is occurring at all transcribed telomeres upon depletion of TRF2. RNA-sequencing of HeLa mRNA, 4 samples: with or without TERRA enrichment by IP (respectively "IP" and "input"), with or without TFR-2 knock-down (respectively "_T" and "_EV").

ORGANISM(S): Homo sapiens

SUBMITTER: Julien Delafontaine 

PROVIDER: E-GEOD-56727 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress