Global gene expression analysis reveals importance of thermal effect in cellular response to millimeter wave exposure

ABSTRACT: To evaluate the effect of millimeter waves (MMW) exposure on the gene expression, we have employed whole genome microarray expression profiling. Neonatal primary Keratinocyte cells pooled from 3 healthy donors were exposed ex vivo, 3 hours at 20 mW/cm². At this condition, corresponding to the maximum power density authorized for public use, MMW exposure induces a significant increase of the temperature and 665 genes were found differentially expressed. To determine the role of hyperthermia in this response, several controls were performed. When the temperature artificially maintained constant, no specific gene modifications were observed after exposure. However, a heat shock control did not mimic exactly the MMW effect: 34-gene signatures were identified between 20 mW/cm2 MMW exposure and

ORGANISM(S): Homo sapiens

SUBMITTER: Denis Habauzit 

PROVIDER: E-GEOD-57135 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress