Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of human HeLa CD4+ cells transfected with parental vector pCep4


ABSTRACT: Expression profiles of HeLa CD4+ cells transfected with parental vector pCep4. Cells are treated with nocodazole and hydroxyurea.

ORGANISM(S): Homo sapiens

SUBMITTER: Winnie Liang 

PROVIDER: E-GEOD-572 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications


<h4>Background</h4>Despite the success of HAART, patients often stop treatment due to the inception of side effects. Furthermore, viral resistance often develops, making one or more of the drugs ineffective. Identification of novel targets for therapy that may not develop resistance is sorely needed. Therefore, to identify cellular proteins that may be up-regulated in HIV infection and play a role in infection, we analyzed the effects of Tat on cellular gene expression during various phases of t  ...[more]

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