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SDF-1 chemokine signaling modulates the apoptotic responses of clathrin-depleted DT40 cells

ABSTRACT: The cell line DKO-S is derived form chicken B-Cell DT40 cells where the clathrin heavy-chain has been placed under the control of a tetracycline-regulatable promoter (Tet-Off). The originally derived cell-line DKO-S underwent apoptosis when clathrin expression was repressed. A cell line, DKO-R, derived from DKO-S cells that was less sensitive to clathrin-depletion. This project explores the differnces in gene expression between DKO-R and DKO-S cells Duplicate samples ofDT40, DKO-S or DKO_R cells either with or without treatment with deoxycyclin are compared as is the expression between DKO-R and DKO-S cell lines

ORGANISM(S): Gallus gallus

SUBMITTER: Antony Jackson

PROVIDER: E-GEOD-57328 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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SDF-1 chemokine signaling modulates the apoptotic responses of clathrin-depleted DT40 cells

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