Aplysia pleural Ganglia 1 Hour After Long-Term Sensitization Training

ABSTRACT: We used a custom-designed microarray and qPCR to characterize the rapid transcriptional response to long-term sensitization training in the marine mollusk Aplysia californica. Aplysia were exposed to repeated noxious shocks to one side of the body (4 ten-second shocks at 90mA, 30 min ISI), a procedure known to induce a transcription-dependent and long-lasting increase in reflex responsiveness that is restricted to the side of training. One hour after training, pleural ganglia from the trained and untrained sides of the body were harvested; these ganglia contain the sensory nociceptors which help mediate the expression of long-term sensitization memory.  Microarray analysis from 8 biological replicates suggests that long-term sensitization training rapidly regulates at least 102 transcr

ORGANISM(S): Aplysia californica

SUBMITTER: Robert Calin-Jageman 

PROVIDER: E-GEOD-57458 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress