Development of a prognostic gene signature in pancreatic cancer
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Dung-Tsa Chen
PROVIDER: E-GEOD-57495 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Prognostic Fifteen-Gene Signature for Early Stage Pancreatic Ductal Adenocarcinoma.
Chen Dung-Tsa DT Davis-Yadley Ashley H AH Huang Po-Yu PY Husain Kazim K Centeno Barbara A BA Permuth-Wey Jennifer J Pimiento Jose M JM Malafa Mokenge M
PloS one 20150806 8
The outcomes of patients treated with surgery for early stage pancreatic ductal adenocarcinoma (PDAC) are variable with median survival ranging from 6 months to more than 5 years. This challenge underscores an unmet need for developing personalized medicine strategies to refine the current treatment decision-making process. To derive a prognostic gene signature for patients with early stage PDAC, a PDAC cohort from Moffitt Cancer Center (n = 63) was used with overall survival (OS) as the primary ...[more]
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