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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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RNA-seq analysis of alternative splicing events in duplicated genes of Arabidopsis thaliana indicates considerable qualitative and quantitative divergence

ABSTRACT: Divergence of alternative splicing in duplicated genes is investigated Three replicates of RNA-seq for Arabidopsis first true leaf tissue

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: David Tack

PROVIDER: E-GEOD-57579 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Transcriptome analysis indicates considerable divergence in alternative splicing between duplicated genes in Arabidopsis thaliana.

Tack David C DC Pitchers William R WR Adams Keith L KL

Genetics 20141016 4

Gene and genome duplication events have created a large number of new genes in plants that can diverge by evolving new expression profiles and functions (neofunctionalization) or dividing extant ones (subfunctionalization). Alternative splicing (AS) generates multiple types of mRNA from a single type of pre-mRNA by differential intron splicing. It can result in new protein isoforms or downregulation of gene expression by transcript decay. Using RNA-seq, we investigated the degree to which altern ...[more]

PMID: 25326238

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