Single-cell analysis reveals prominent classes within the planarian stem cell compartment

ABSTRACT: Single cell qPCR analysis identified two prominent expression signatures within the planarian stem cells, the neoblasts. RNAi against zinc finger protein zfp-1 results in elimination of one of the two classes. Worms were treated with RNAi by feeding. X1 or X2 cells were isolated by FACS, or blastemas were dissected. mRNA libraries were sequenced.

ORGANISM(S): Schmidtea mediterranea

SUBMITTER: Josien van Wolfswinkel 

PROVIDER: E-GEOD-58057 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress