Transcriptome signatures for robustness of Lactococcus lactis MG1363

ABSTRACT: This study describes a transcriptome-phenotype matching approach in which the starter L. lactis MG1363 was fermented under a variety of conditions that differed in the levels of oxygen and/or salt, as well as the fermentation pH and temperature. Samples derived from these fermentations in the exponential phase of bacterial growth were analyzed by full-genome transcriptomics and the assessment of heat and oxidative stress phenotypes. Variations in the fermentation conditions resulted in up to 1000-fold differences in survival during heat and oxidative stress. More specifically, aeration during fermentation induced protection against heat stress, whereas a relatively high fermentation temperature resulted in enhanced robustness towards oxidative stress. Concomitantly, oxygen levels and ferme

ORGANISM(S): Lactococcus lactis subsp. cremoris MG1363

SUBMITTER: Annereinou Dijkstra 

PROVIDER: E-GEOD-58284 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress