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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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The human skeletal muscle transcriptome – sex differences, alternative splicing and tissue homogeneity assessed with RNA sequencing

ABSTRACT: The amount of RNA sequencing data on skeletal muscle is very limited. We have analyzed a large set of human muscle biopsy samples and provide extensive information on the baseline skeletal muscle transcriptome, including completely novel protein-coding transcripts. Analyze of transcriptome in 23 skeletal muscle biopsy samples from six individuals. Four biopsies from each subject, two biopsies from each leg (except subject 6 which has only three biopsies in total). This experiment is linked to E-GEOD-58608.

ORGANISM(S): Homo sapiens

SUBMITTER: Joakim Lundeberg

PROVIDER: E-GEOD-58387 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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The human skeletal muscle transcriptome: sex differences, alternative splicing, and tissue homogeneity assessed with RNA sequencing.

Lindholm Malene E ME Huss Mikael M Solnestam Beata W BW Kjellqvist Sanela S Lundeberg Joakim J Sundberg Carl J CJ

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20140711 10

Human skeletal muscle health is important for quality of life and several chronic diseases, including type II diabetes, heart disease, and cancer. Skeletal muscle is a tissue widely used to study mechanisms behind different diseases and adaptive effects of controlled interventions. For such mechanistic studies, knowledge about the gene expression profiles in different states is essential. Since the baseline transcriptome has not been analyzed systematically, the purpose of this study was to prov ...[more]

PMID: 25016029

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The human skeletal muscle transcriptome assessed with RNA sequencing

Project description:The amount of RNA sequencing data on skeletal muscle is very limited. We have analyzed a large set of human muscle biopsy samples and provide extensive information on the baseline skeletal muscle transcriptome, including completely novel protein-coding transcripts. Analyze of transcriptome in 24 skeletal muscle biopsy samples, 12 individuals and one biopsy per leg per individual. This experiment is linked to E-GEOD-58387.

2014-07-15 | E-GEOD-58608 | biostudies-arrayexpress

Dynamics of the human skeletal muscle transcriptome in response to exercise training - part 1

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The human skeletal muscle transcriptome assessed with RNA sequencing

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