ABL Tyrosine Kinase Phosphorylates DGCR8 to Stimulate MicroRNA Processing in DNA Damage Response

ABSTRACT: miR-seq to find miRs that are induced by DNA damage and whose induction requires ABL kinase activity Use p53-inactive HEK293T cells. Use doxorubicin to induce DNA damage. Use imatinib co-treatment to inhibit ABL kinase activity

ORGANISM(S): Homo sapiens

SUBMITTER: Jean Wang 

PROVIDER: E-GEOD-59028 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress