Transcriptomic analysis of F. oxysporum M-NM-^Tcon7-1 mutant during in vitro growth

ABSTRACT: Previous studies have demonstrated the essential role of morphogenetic regulation in Fusarium oxysporum pathogenesis, including processes such as cell-wall biogenesis, cell division and differentiation of infection-like structures. We identified three F. oxysporum genes encoding predicted transcription factors showing significant identities to Magnaporthe oryzae Con7p, Con7-1, plus two identical copies of Con7-2. Targeted deletion of con7-1 produced non-pathogenic mutants with altered morphogenesis, including defects in cell wall structure, polar growth, hyphal branching and conidiation. By contrast, simultaneous inactivation of both con7-2 copies caused no detectable defects in the resulting mutants. Comparative microarray-based gene expression analysis indicated that Con7-1 modulates the

ORGANISM(S): Fusarium oxysporum

SUBMITTER: Carmen Ruiz Roldan 

PROVIDER: E-GEOD-59311 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress