Effect of Dnmt3a deletion on the global DNA methylation status of osteoclasts

ABSTRACT: Epigenetic regulation is a fundamental mechanism mediating various cellular processes. However, epigenetic mechanisms in osteoclastogenesis remain to be elucidated. We performed MBD-seq analysis to investigate DNA methylation in osteoclasts derived from wild-type and osteoclast-specific Dnmt3a knockout mice. Examination of DNA methylation in 2 cell types.

ORGANISM(S): Mus musculus

SUBMITTER: Keizo Nishikawa 

PROVIDER: E-GEOD-59388 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress