Expression data from heterotopically grafted mouse small intestinal epithelium and the normal colonic epithelium

ABSTRACT: Epithelia of small and large intestines differ in their structures and functions. Such heterogeneity between these two epithelial tissues might be controlled by both epithelium-intrinsic and -extrinsic programs. By employing the cell transplantation technique developed in our laboratory, we investigated how adult SI epithelial cells behave when heterotopically transplanted onto colon. Then the gene expression profiles of small intestinal epithelium heterotopically transplanted onto colon and control colonic epithelium were compared. We used laser capture microdissection and microarray analysis to compare the global gene expression profiles of small intestinal epithelium in the heterotopically grafted tissues and control colonic epithelium. Dissected epithelia obtained from serial sections

ORGANISM(S): Mus musculus

SUBMITTER: Tetsuya Nakamura 

PROVIDER: E-GEOD-59410 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress