Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Gene Expression Profiling of Hepatocellular Carcinoma


ABSTRACT: To identify the prognostic subtypes of hepatocellular carcinoma with potential progenitor cell origin. Keywords: disease state design We used our in-house oligonucleotide microarray data of 238 HBV-positive HCC cases.

ORGANISM(S): Homo sapiens

SUBMITTER: Xin Wei Wang 

PROVIDER: E-GEOD-5975 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Gene expression profiling reveals potential biomarkers of human hepatocellular carcinoma.

Jia Hu-Liang HL   Ye Qing-Hai QH   Qin Lun-Xiu LX   Budhu Anuradha A   Forgues Marshonna M   Chen Yidong Y   Liu Yin-Kun YK   Sun Hui-Chuan HC   Wang Lu L   Lu Hong-Zhou HZ   Shen Fang F   Tang Zhao-You ZY   Wang Xin Wei XW  

Clinical cancer research : an official journal of the American Association for Cancer Research 20070201 4


<h4>Purpose</h4>Hepatocellular carcinoma (HCC), a common cancer worldwide, has a dismal outcome partly due to the poor identification of early-stage HCC. Currently, one third of HCC patients present with low serum alpha-fetoprotein (AFP) levels, the only clinically available diagnostic marker for HCC. The aim of this study was to identify new diagnostic molecular markers for HCC, especially for individuals with low serum AFP.<h4>Experimental design</h4>We used the microarray technique to determi  ...[more]

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