Insights into the epigenomic landscape of the human malaria vector Anopheles gambiae
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ABSTRACT:
ORGANISM(S): Anopheles gambiae
SUBMITTER: Elena Gomez-Diaz
PROVIDER: E-GEOD-59773 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Insights into the epigenomic landscape of the human malaria vector Anopheles gambiae.
Gómez-Díaz Elena E Rivero Ana A Chandre Fabrice F Corces Victor G VG
Frontiers in genetics 20140815
The epigenome of the human malaria vector Anopheles gambiae was characterized in midgut cells by mapping the distribution and levels of two post-translational histone modifications, H3K27ac and H3K27me3. These histone profiles were then correlated with levels of gene expression obtained by RNA-seq. Analysis of the transcriptome of A. gambiae midguts and salivary glands led to the discovery of 13,898 new transcripts not present in the most recent genome assembly. A subset of these transcripts is ...[more]
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