Gene expression profiling of preneoplastic Lgr5-creERT2/PIK3CAH1047R mammary subsets

ABSTRACT: This study examined the effect of mutant PIK3CAH1047R expression in mammary subsets of preneoplastic mammary glands from Lgr5-creERT2/PIK3CA H1047R mice Mammary cell subpopulations were isolated from Lgr5-creERT2/PIK3CA H1047R and Lgr5-creERT2 control animals 4 weeks after activation of PIK3CA H1047R transgene expression by Tamoxifen injection. Pooled mammary glands of 2-3 estrus-synchronized mice per genotype were sorted in 3 independent sortings and used for microarray analysis (24 samples in total).

ORGANISM(S): Mus musculus

SUBMITTER: Tim Roloff 

PROVIDER: E-GEOD-59870 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress