MicroRNAome of Spodoptera frugiperda cells (Sf9) and its alteration following baculovirus infection

ABSTRACT: MicroRNAs (miRNAs) as small non-coding RNAs play important roles in many biological processes such as development, cell signalling and immune response. Studies also suggest that miRNAs are important in host–virus interactions where the host limits virus infection by differentially expressing miRNAs that target essential viral genes. Here, we identified conserved and new miRNAs from Spodoptera frugiperda cells (Sf9) using a combination of deep sequencing and bioinformatics as well as experimental approaches. S. frugiperda miRNAs share common features of miRNAs in other organisms, such as uracil (U) at the 59 end of miRNA. The 59 ends of the miRNAs were more conserved than the 39 ends, revealing evolutionary protection of the seed region in miRNAs. The predominant miRNAs were found to be con

ORGANISM(S): Spodoptera frugiperda

SUBMITTER: Kayvan Etebari 

PROVIDER: E-GEOD-60064 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress