MicroRNAs maintain bivalency in mouse embryonic stem cells [ChIP-seq]

ABSTRACT: The protein Dicer is required for microRNA (miRNA) biogenesis, and therefore Dicer-deficient cells lack all mature, functional miRNAs. Here we investigated the binding of the PRC2 component Ezh2 in wildtype and Dicer-deficient mouse embryonic stem cells genomewide using ChIP-sequencing analysis. Examination of Ezh2 binding in mouse ES cells either proficient (wildtype) or deficient (KO) of the protein Dicer

ORGANISM(S): Mus musculus

SUBMITTER: Gopuraja Dharmalingam 

PROVIDER: E-GEOD-60160 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress