Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Genome-wide analysis of the lsm4 and lsm5 mutant transcriptomes


ABSTRACT: The goal of this study was to compare the transcriptional profile (RNA-seq) of lsm4 and lsm5 Arabidopsis mutants with their respective wild type plants grown under continuous light conditions lsm4 and lsm5 mutant plants were grown together with their respective wild type plants for two weeks under continuous white light at 22 degrees centigrades and the transcriptional profile of these plants was analyzed using RNA-seq.

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Marcelo Yanovsky 

PROVIDER: E-GEOD-60387 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Role for LSM genes in the regulation of circadian rhythms.

Perez-Santángelo Soledad S   Mancini Estefanía E   Francey Lauren J LJ   Schlaen Ruben Gustavo RG   Chernomoretz Ariel A   Hogenesch John B JB   Yanovsky Marcelo J MJ  

Proceedings of the National Academy of Sciences of the United States of America 20141006 42


Growing evidence suggests that core spliceosomal components differentially affect RNA processing of specific genes; however, whether changes in the levels or activities of these factors control specific signaling pathways is largely unknown. Here we show that some SM-like (LSM) genes, which encode core components of the spliceosomal U6 small nuclear ribonucleoprotein complex, regulate circadian rhythms in plants and mammals. We found that the circadian clock regulates the expression of LSM5 in A  ...[more]

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