Gene expression alteration in chondrocyte by HES1 overexpression

ABSTRACT: To investigate target molecules of HES1, we transduced GFP or HES1 into mouse chondrocyte cell line ATDC5, and performed the microarray analysis. HES1 overexpression increased inflammation-related genes including Il6 and Il1rl1. We established stable ATDC5 cells overexpressing GFP or HES1 by lentiviral transduction. We harvested mRNA from these cells, and performed microarray analysis.

ORGANISM(S): Mus musculus

SUBMITTER: Taku Saito 

PROVIDER: E-GEOD-60737 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress