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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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14-3-3ζ controls adipocyte progenitor cell cycle and differentiation via Gli3-dependent p27Kip expression

ABSTRACT: 14-3-3 proteins facilitate cytoplasmic-nuclear shuttling of transcription factors.Adipocyte differentiation requires the function of critical transcription factors to drive the development of a mature adipocyte. The aim of the study was to investigate if 14-3-3ζ is required for the adipogenic transcriptional program. Examination of the transcriptome in siCon- and si14-3-3ζ-transfected 3T3-L1 cells undergoing differentiation at t=0, 24, and 48 hours.

ORGANISM(S): Mus musculus

SUBMITTER: Gareth Lim

PROVIDER: E-GEOD-60745 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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