Inflammatory and immune responses in lymph nodes of Iberian red deer infected with Mycobacterium bovis.

ABSTRACT: Bovine tuberculosis (bTB), caused by Mycobacterium bovis (Mycobacterium tuberculosis complex), is a zoonotic disease that affects cattle and wildlife worldwide. In some regions of Spain, Iberian red deer (Cervus elaphus hispanicus) can serve as reservoir of infection, thus increasing the risk of human and cattle exposure and infection. Mesenteric lymph nodes are naturally infected with M. bovis in Iberian red deer, in which the digestive route of infection is particularly important in Mediterranean Spain. In this study we characterized the differential expression of inflammatory and immune response genes in mesenteric lymph nodes of Iberian red deer naturally infected with M. bovis using a Ruminant Immuno-inflammatory Gene Universal Array (RIGUA) and real-time RT-PCR. Of the 600 genes that

ORGANISM(S): Cervus elaphus hispanicus

SUBMITTER: Patricia Ayoubi 

PROVIDER: E-GEOD-6083 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress