Molecular regulation of enhanced muscle mass in developing Blond Aquitaine foetuses compared to Charolais

ABSTRACT: Background : The Blonde Aquitaine (BA) is a French beef breed with enhanced muscularity of unknown genetic origin. Targeted sequencing has shown that the BA is not a carrier of any of the bovine MSTN mutations. At the protein level the BA shows a transition to a faster muscle isoform phenotype with a greater proportion of type IIX and a smaller proportion of type I fibres than comparison Charolais (CH). Associated modifications in the activity of oxidative and glycolytic enzymes were also previously detected. Collectively, these changes are often observed in breeds of production species selected for enhanced growth and efficiency, but the underlying molecular mechanisms are unknown. Method : We examined the transcriptome of the Longissimus thoracis muscle at 4 gestational stages (110, 180,

ORGANISM(S): Bos taurus

SUBMITTER: Isabelle Cassar-Malek 

PROVIDER: E-GEOD-60844 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress