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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Gcn5 and PCAF negatively regulate interferon β production through HAT-independent inhibition of TBK1

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: Kai Ge

PROVIDER: E-GEOD-60969 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gcn5 and PCAF negatively regulate interferon β production through HAT-independent inhibition of TBK1 [ChIP-Seq]

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2014-09-03 | E-GEOD-60967 | biostudies-arrayexpress

Gcn5 and PCAF negatively regulate interferon-β production through HAT-independent inhibition of TBK1.

Project description: Not available

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Gcn5 and PCAF negatively regulate interferon β production through HAT-independent inhibition of TBK1

Project description:This SuperSeries is composed of the SubSeries listed below.

2014-09-03 | GSE60969 | GEO

Gcn5 and PCAF negatively regulate interferon β production through HAT-independent inhibition of TBK1 [RNA-Seq]

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Project description:Gcn5/PCAF double knockout (dKO) leads to loss of the global H3K9ac. RNA-Seq was performed to define the changes of gene expression in response to Gcn5/PCAF deletion and H3K9ac loss PCAF-/-;Gcn5f/D MEFs were infected with retroviral Cre to delete Gcn5 to generate Gcn5/PCAF dKO cells, followed by RNA-Seq analysis using spike-in RNA as controls

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