Molecular portraits of human breast tumors
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: C Perou
PROVIDER: E-GEOD-61 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Molecular portraits of human breast tumours.
Perou C M CM Sørlie T T Eisen M B MB van de Rijn M M Jeffrey S S SS Rees C A CA Pollack J R JR Ross D T DT Johnsen H H Akslen L A LA Fluge O O Pergamenschikov A A Williams C C Zhu S X SX Lønning P E PE Børresen-Dale A L AL Brown P O PO Botstein D D
Nature 20000801 6797
Human breast tumours are diverse in their natural history and in their responsiveness to treatments. Variation in transcriptional programs accounts for much of the biological diversity of human cells and tumours. In each cell, signal transduction and regulatory systems transduce information from the cell's identity to its environmental status, thereby controlling the level of expression of every gene in the genome. Here we have characterized variation in gene expression patterns in a set of 65 s ...[more]
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