A food deprivation affects the miRNome in the lactating goat mammary gland

ABSTRACT: Nutrition affects milk composition influencing its nutritional properties. Nutrition also modifies the expression of mammary genes, whose regulation is not completely known. MicroRNAs (miRNA) are small non-coding RNA that work as important post-transcriptional gene expression regulators by targeting messenger RNAs. Our goal was to characterize miRNA whose expression is regulated by nutrition in the lactating goat mammary gland, and which may give clues to decipher the regulations of milk components biosynthesis and secretion. Using high-throughput sequencing technology, miRNomes of the lactating mammary gland have been established from 4 goats fed ad libitum and 6 goats food deprived during 48h. Food deprivation affected the expression of 30 miRNA (padj<0.1), 16 were downregulated and 14 w

ORGANISM(S): Capra hircus

SUBMITTER: Sylvain Marthey 

PROVIDER: E-GEOD-61025 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress