Transcription profiling of rat female mouse lung tumors in rodent cancer bioassays - a 13 chemical training set

ABSTRACT: The primary goal of toxicology and safety testing is to identify agents that have the potential to cause adverse effects in humans. Unfortunately, many of these tests have not changed significantly in the past 30 years and most are inefficient, costly, and rely heavily on the use of animals. The rodent cancer bioassay is one of these safety tests and was originally established as a screen to identify potential carcinogens that would be further analyzed in human epidemiological studies. Today, the rodent cancer bioassay has evolved into the primary means to determine the carcinogenic potential of a chemical and generate quantitative information on dose-response behavior in chemical risk assessments. Due to the resource-intensive nature of these studies, each bioassay costs $2 to $4 mill

ORGANISM(S): Mus musculus

SUBMITTER: Russell Scott Thomas 

PROVIDER: E-GEOD-6116 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress