Ontology highlight
ABSTRACT:
ORGANISM(S): Streptomyces lividans
SUBMITTER: Juan Oliveros
PROVIDER: E-GEOD-61447 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
PloS one 20150722 7
Streptomyces lividans is considered an efficient host for the secretory production of homologous and heterologous proteins. To identify possible bottlenecks in the protein production process, a comparative transcriptomic approach was adopted to study cellular responses during the overproduction of a Sec-dependent model protein (alpha-amylase) and a Tat-dependent model protein (agarase) in Streptomyces lividans. The overproduction of the model secretory proteins via the Sec or the Tat route in S. ...[more]