Enhanced adult hippocampal neurogenesis in mice fed the marine-plant derived astaxanthin supplement: A DNA microarray-based analyses

ABSTRACT: Astaxanthin (ASX), the most powerful antioxidant within carotenoids, has not only anti-oxidative stress and anti-infammation, but also neuroprotective effects in the preventatin of oxidative damage on various neurodegenerative diseases in vivo and in vitro. Recent studies demonstrated that ASX enhanced learning and memory performance in human and animal, but its beneficial effects on neuronal mechanism are unknown. Moreover, it is unclelar delving further into ASX-induced the possible molecular mechanisim on adult hippocampal neurogenesis (AHN). Here, we investigated whether ASX enhances AHN depend on concentration, and their related to potential molecular pathway using DNA microarray analysis. Adult male C57BL/6J mice were divided according to different consistency 0% (CON), 0.02%, 0.1%,

ORGANISM(S): Mus musculus

SUBMITTER: Randeep Rakwal 

PROVIDER: E-GEOD-62197 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress