Comprehensive Serial Analysis of Gene Expression of the Cervical Epithelium Transcriptome
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Ashleen Shadeo
PROVIDER: E-GEOD-6252 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Up regulation in gene expression of chromatin remodelling factors in cervical intraepithelial neoplasia.
Shadeo Ashleen A Chari Raj R Lonergan Kim M KM Pusic Andrea A Miller Dianne D Ehlen Tom T Van Niekerk Dirk D Matisic Jasenka J Richards-Kortum Rebecca R Follen Michele M Guillaud Martial M Lam Wan L WL MacAulay Calum C
BMC genomics 20080204
<h4>Background</h4>The highest rates of cervical cancer are found in developing countries. Frontline monitoring has reduced these rates in developed countries and present day screening programs primarily identify precancerous lesions termed cervical intraepithelial neoplasias (CIN). CIN lesions described as mild dysplasia (CIN I) are likely to spontaneously regress while CIN III lesions (severe dysplasia) are likely to progress if untreated. Thoughtful consideration of gene expression changes pa ...[more]
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