Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Mehmet Somel
PROVIDER: E-GEOD-6285 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Somel Mehmet M Creely Hilliary H Franz Henriette H Mueller Uwe U Lachmann Michael M Khaitovich Philipp P Pääbo Svante S
PloS one 20080130 1
Although the human diet is markedly different from the diets of closely related primate species, the influence of diet on phenotypic and genetic differences between humans and other primates is unknown. In this study, we analyzed gene expression in laboratory mice fed diets typical of humans and of chimpanzees. The effects of human diets were found to be significantly different from that of a chimpanzee diet in the mouse liver, but not in the brain. Importantly, 10% of the genes that differ in t ...[more]