Interspecific Introgressive Origin of Genomic Diversity in the House Mouse

ABSTRACT: We report on a genome-wide scan for introgression in the house mouse (Mus musculus domesticus) involving the Algerian mouse (Mus spretus), using 20 samples from the ranges of sympatry and allopatry. Our analysis reveals significant variability in introgression signatures along the genomes, as well as across the samples. We find that fewer than half of the chromosomes in each genome harbor all detectable introgression. Further, a surprising result is that European mice carry more M. spretus alleles than the sympatric African ones. Using the length distribution and sharing patterns of introgressed genomic tracts across the samples, we propose three hypotheses. First, at least three distinct hybridization events involving M. spretus have occurred, one of which is ancient, and the other two ar

ORGANISM(S): Mus musculus domesticus

SUBMITTER: Kevin Liu 

PROVIDER: E-GEOD-62906 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress