Transcription profiling of mouse epithelium and mesenchyme to study the gene expression profiles in these two compartments

ABSTRACT: During organogenesis of the intestine, reciprocal crosstalk between the endodermally-derived epithelium and the underlying mesenchyme is required for regional patterning and proper differentiation. Though both of these tissue layers participate in patterning, the mesenchyme is thought to play a prominant role in the determination of epithelial phenotype during development and in adult life. However, the molecular basis of this instructional dominance is unclear. In fact, surprisingly little is known about the cellular origins of many of the critical signaling molecules and the gene transcriptional events that they impact. Here, we profile genes that are expressed in separated mesenchymal and epithelial compartments of the perinatal mouse intestine. The data indicate that the vast majori

ORGANISM(S): Mus musculus

SUBMITTER: Xing Li 

PROVIDER: E-GEOD-6383 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress