Transcription profiling of human A549 NSCLC cells cisplatin induced changes
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Gabriela Almeida
PROVIDER: E-GEOD-6410 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Multiple end-point analysis reveals cisplatin damage tolerance to be a chemoresistance mechanism in a NSCLC model: implications for predictive testing.
Almeida Gabriela M GM Duarte Tiago L TL Farmer Peter B PB Steward William P WP Jones George D D GD
International journal of cancer 20080401 8
Systemic chemotherapy is extensively used in cancer therapy, however, for many treatments' response rates are limited. Furthermore, certain regimens are frequently associated with significant morbidity and occasional mortality. Consequently, when alternative options exist, it is desirable to reserve a particular chemotherapy for those patients whose tumours will respond. Therefore, attention is turning to the development of techniques that could provide predictive information regarding a tumour' ...[more]
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