Genome-wide mapping of DNA hydroxymethylation in osteoarthritic chondrocytes [methylation]

ABSTRACT: Examination of the genome-wide distribution of 5hmC in osteoarthritic chondrocytes compared to normal chondrocytes in order to elucidate the effect on OA-specific gene expression. 5hmC-sequencing was performed and data was compared with microarray gene expression data to identify genes with differential expression between normal and OA chondrocytes that are potentially under epigenetic regulation. High-throughput sequencing of 5hmC in 4 normal and 4 OA chondrocyte samples.

ORGANISM(S): Homo sapiens

SUBMITTER: Sarah Taylor 

PROVIDER: E-GEOD-64393 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress