Differentially expressed genes between osteochondroprogenitor sub-populations

ABSTRACT: Cell based bone regeneration strategies offer promise for traumatic bone injuries, congenital defects, non-union fractures and other skeletal pathologies. Postnatal bone remodeling and fracture healing provide evidence that an osteochondroprogenitor cell is present in adult life which can differentiate to remodel or repair the fractured bone. However, cell based skeletal repair in the clinic is still in its infancy mostly due to poor characterization of progenitor cells and lack of knowledge about their in vivo behavior. Here we took a combined approach of high throughput screening, flow based cell sorting and in vivo transplantation to identify markers that identify osteochondroprogenitor cells. We show that the presence of tetraspanin CD9 enriches for osteochondroprogenitors within CD105

ORGANISM(S): Mus musculus

SUBMITTER: Anju Aingh 

PROVIDER: E-GEOD-64406 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress