Rescue of CD8+ T cell vaccine memory in mice following sublethal g radiation exposure

ABSTRACT: In two disparate models, we show that rapid revaccination following sublethal gamma radiation exposure rescues memory CD8+ T cell Responses. To investigate the mechanism of rescue we performed RNA microarray analyses to identify whether there was a genetic “signature” of rescue. mRNA was obtained from whole spleens 6 hrs after revaccination with LM-DActA at D1 and D4 PI for RNA microarray analysis

ORGANISM(S): Mus musculus

SUBMITTER: abdel Elkahloun 

PROVIDER: E-GEOD-64434 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress