Expression data from pancreatic beta cells isolated from differentially weaned mice.
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ABSTRACT: Transcriptome analysis reveals that in pancreatic beta cells weaning increases the expression of genes involved in replication licensing, suggesting a mechanism to increased responsiveness to the mitogenic activity of high glucose. ? cells were sorted from dissociated islets of P25 insulin-Cre; Rosa26-LSL-YFP mice (Gannon et al., 2000; Srinivas et al., 2001) that were either suckling or prematurely weaned at P18. YFP+ FACS-sorted cells were subjected for RNA extraction and hybridization on Affymetrix microarrays
ORGANISM(S): Mus musculus
SUBMITTER: Miri Stolovich-Rain
PROVIDER: E-GEOD-64524 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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