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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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The UBC-40 Urothelial Bladder Cancer Cell Line Index

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Enrique Carrillo de Santa Pau

PROVIDER: E-GEOD-64573 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.

Earl Julie J Rico Daniel D Carrillo-de-Santa-Pau Enrique E Rodríguez-Santiago Benjamín B Méndez-Pertuz Marinela M Auer Herbert H Gómez Gonzalo G Grossman Herbert Barton HB Pisano David G DG Schulz Wolfgang A WA Pérez-Jurado Luis A LA Carrato Alfredo A Theodorescu Dan D Chanock Stephen S Valencia Alfonso A Real Francisco X FX

BMC genomics 20150522

<h4>Background</h4>Urothelial bladder cancer is a highly heterogeneous disease. Cancer cell lines are useful tools for its study. This is a comprehensive genomic characterization of 40 urothelial bladder carcinoma (UBC) cell lines including information on origin, mutation status of genes implicated in bladder cancer (FGFR3, PIK3CA, TP53, and RAS), copy number alterations assessed using high density SNP arrays, uniparental disomy (UPD) events, and gene expression.<h4>Results</h4>Based on gene mut ...[more]

PMID: 25997541

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