Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Adrianus Boon
PROVIDER: E-GEOD-64750 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Journal of virology 20090812 20
Despite the prevalence of H5N1 influenza viruses in global avian populations, comparatively few cases have been diagnosed in humans. Although viral factors almost certainly play a role in limiting human infection and disease, host genetics most likely contribute substantially. To model host factors in the context of influenza virus infection, we determined the lethal dose of a highly pathogenic H5N1 virus (A/Hong Kong/213/03) in C57BL/6J and DBA/2J mice and identified genetic elements associated ...[more]