Expression data from Plasmodium falciparum schizonts

ABSTRACT: During intra-erythrocytic development, late asexually replicating Plasmodium falciparum parasites sequester from peripheral circulation. This facilitates chronic infection and is linked to severe disease and organ-specific pathology including cerebral and placental malaria. Immature gametocytes M-bM-^@M-^S sexual stage precursor cells M-bM-^@M-^S likewise disappear from circulation. Recent work has demonstrated that these sexual stage parasites are located in the hematopoietic system of the bone marrow before mature gametocytes are released into the blood stream to facilitate mosquito transmission. However, as sequestration occurs only in vivo and not during in vitro culture, the mechanisms by which it is regulated and enacted (particularly by the gametocyte stage) remain poorly understood

ORGANISM(S): Plasmodium falciparum

SUBMITTER: Matthias Marti 

PROVIDER: E-GEOD-64887 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress