Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline

ABSTRACT: We identify perhexiline, a small molecule inhibitor of mitochondrial carnitine palmitoyltransferase-1, as a HES1-signature antagonist drug with robust antileukemic activity against NOTCH1 induced leukemias in vitro and in vivo. RNA-Seq from CUTLL1 cell lines treated with Perhexiline or vehicle for 3 days

ORGANISM(S): Homo sapiens

SUBMITTER: Alberto Ambesi-Impiombato 

PROVIDER: E-GEOD-66014 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress