Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Lee Vandivier
PROVIDER: E-GEOD-66224 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Vandivier Lee E LE Campos Rafael R Kuksa Pavel P PP Silverman Ian M IM Wang Li-San LS Gregory Brian D BD
The Plant cell 20151111 11
Posttranscriptional chemical modification of RNA bases is a widespread and physiologically relevant regulator of RNA maturation, stability, and function. While modifications are best characterized in short, noncoding RNAs such as tRNAs, growing evidence indicates that mRNAs and long noncoding RNAs (lncRNAs) are likewise modified. Here, we apply our high-throughput annotation of modified ribonucleotides (HAMR) pipeline to identify and classify modifications that affect Watson-Crick base pairing a ...[more]