Transcriptional profiling of small intestinal crypts from mice treated with Notch blocking antibodies or Notch blocking antibodies in combination with an Lrp6 blocking antibody.

ABSTRACT: The goal of this study was to identify genes that are differentially expressed during a 24 hour Notch blockade and whether a Wnt antagonist (anti-Lrp6) could block this effect. 3 condition experiment, Control untreated compared to N1N2 treated, and N1N2 treated compared to N1N2_Lrp6 treated. 5 biological replicates per condition.

ORGANISM(S): Mus musculus

SUBMITTER: Brian Biehs 

PROVIDER: E-GEOD-66751 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress