Transcriptomic signatures of Auger electron radioimmunotherapy using nuclear targeting 111In-trastuzumab for potential combination therapies

ABSTRACT: The aim of this study was to identify targetable molecular signatures for enhancing the cytotoxic effects of In-111-trastuzumab-NLS using microarray technology. Changes in gene expression in SKBR3 cells untreated or treated with unlabeled or In-111-labeled antibodies for 7 days were measured. Three independent experiments in each condition were performed.

ORGANISM(S): Homo sapiens

SUBMITTER: Kazuhiro DAINO 

PROVIDER: E-GEOD-67193 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress